University of New South Wales - School of Risk and Safety Sciences

Ph.D. (UNSW), MEnvStud, BAppSc(Hons), Grad Cert(Tert Teaching), MRACI
Phone : 938 54200
Email : a.hayes@unsw.edu.au

Dr. Hayes is currently on maternity leave

Dr Amanda Hayes is a Lecturer at the School of Risk and Safety Sciences and Manager of the Chemical Safety and Applied Toxicology (CSAT) Laboratories. Amanda supervises PhD, Masters and Honours students from CSAT Labs and coordinates and lectures to undergraduate and postgraduate students from the Safety Science Program. Amanda's personal research area focuses on in vitro toxicity testing using human cell lines and in vitro percutaneous absorption through human skin of pharmaceuticals, cosmetics and natural products especially essential oils.

Before returning to UNSW in July 2003, Amanda held a Lecturing position at the School of Medicine, James Cook University, Townsville where she was involved in curriculum development and teaching of Dermatology, Molecular Sciences and Immunology for students in years 1-3 of the undergraduate Medical Programme. Amanda coordinated the Year 1 Medical Electives Programme and was elected to the inaugural Research and Training Committee and the BMedSc Committee of the School of Medicine.

Amanda completed an industry funded PhD at UNSW in 2000 titled " Chemistry, Efficacy and Toxicity of Selected Australian Essential Oils". Amanda was the Principal Investigator of this Collaborative Research Grant between the Health Care Company Blackmores Ltd, the Univeristy of Western Sydney Hawkesbury and UNSW. Prior to her PhD Amanda worked for Blackmores in the Technical Department as part of the Quality Assurance Team at their manufacturing site in Sydney.

Recent Publications (2003-2006)

Selected Referred Publications (2003-2006):

Bakand, S. Winder, C. Khalil, C. and Hayes, A. An experimental in vitro model for dynamic direct exposure of human cells to airborne contaminants. Toxicology Letters. In press.
Lestari, F., Markovic, B., Green, A., Chattopadhyay, G. and Hayes, A. comparative assessment of three in vitro exposure methods for combustion toxicity. Journal of Applied Toxicology, 25: In press.
Lestari, F., Green, A.R., Chattopadhyay, G. and Hayes, A.J. An alternative method for fire smoke toxicity assessment using human lung cells. Fire Safety Journal. In press.
Bakand, S. Winder, C., Khalil, C. and Hayes, A., (2006). A novel in vitro exposure technique for toxicity assessment of volatile organic compounds. Journal of Environmental Monitoring. 8:1, 100-105.
Lestari, F., Hayes, A. J., Green A. R. and Markovic, B. (2005) In vitro cytotoxicity of selected chemicals commonly produced during fire combustion using human cell lines. Toxicology In Vitro. 19(5): 653-663.
Bakand, S., Hayes, A., Winder, C., Khalil, C. and Markovic, B. (2005). In vitro cytotoxicity testing of airborne formaldehyde collected in serum-free culture media. Toxicology and Inhalation Health, 21:1-8.
Bakand, S., Winder, C., Khalil, C. and Hayes, A., (2005). Toxicity assessment of industrial chemicals and airborne contaminants: transition from in vivo to in vitro test methods: A review. Inhalation Toxicology 17:775-787.
Hayes, A. J, and Markovic, B. (2003) Toxicity of Australian essential oil Backhousia citriodora (Lemon myrtle) 2. Absorption and histopathology following exposure to human skin. Food and Chemical Toxicology, 41:1409-1416.

Selected Conference Presentations (2003-2005):

Bakand, S., Winder, C., Khalil, C. and Hayes, A., (2005). Toxicity assessment of workplace air contaminants using a novel in vitro cell culture technique. The NSW SIA Safety Conference. 26-28 October, Sydney, Australia.
Bakand, S., Winder, C., Khalil, C. and Hayes, A., (2005). Novel in vitro exposure techniques for toxicity testing and biomonitoring of airborne contaminants. The Fifth World Congress on Alternatives and Animal Use in the Life Sciences, 21-25 August, Berlin, Germany. Alternatives To animal Experimentation (ALTEX), Vol. 22: 184.
Lestari , F., Hayes, A. J., Green , A. R., and Chattopadhyay, G. (2005). Assessing the toxicity of smoke derived from polymer combustion using human lung cells (A549). Oral presentation. The Fifth World Congress on Alternatives and Animal Use in the Life Sciences, 21-25 August, Berlin, Germany. Alternatives To animal Experimentation (ALTEX), Vol. 22.
Azzi, R., Hayes, A., Winder, C., and Khalil, C. (2005) An in vitro cytotoxicity study of the interactive effect of 24 binary and ternary mixtures from the GHS classification groups. Oral presentation. The Fifth World Congress on Alternatives and Animal Use in the Life Sciences, 21-25 August, Berlin, Germany. Alternatives To animal Experimentation (ALTEX), Vol. 22.
Bakand, S, Winder, C., Khalil, C. and Hayes, A. (2005). A novel in vitro exposure technique for toxicity assessment of volatile organic compounds. Fifth International Symposium on Modern Principles of Air Monitoring, June 12-16. Loen, Norway
Hayes, A. J. (2005). Assessing the dermal toxicity of natural products using percutaneous absorption and histopathology. Australian Society Cosmetic Chemists- National Conference, Brisbane.
Bakand, S., Winder, C., Khalil, C. and Hayes, A., (2004). Correlation of in vitro and published in vivo toxicity data for workplace chemical contaminants. The 2nd Australian Health and Medical Research (AHMR) Congress. November 21-26. Sydney.
Bakand, S., Hayes, A., Winder, C. and Khalil, C. (2004). In vitro cytotoxicity of formaldehyde and glutaraldehyde mixtures in human cells. Oral presentation in The 6th ICOH International Conference on Occupational Health for Health Care Workers and the 24th UOEH International Symposium. October 8-10, Fukuoka, Japan.
Bakand, S., Winder, C. and Hayes, A. (2004). Development of in vitro methods for toxicity measurement of workplace air toxicants. Australia’s Biotechnology Organization NSW Conference. 27th August. Powerhouse Museum, Sydney.
Bakand, S., Winder, C. and Hayes, A. (2004). The commercial potential of in vitro methods using human cells as an alternative for toxicity assessment of unknown chemicals. Australia’s Biotechnology Organization NSW Conference. 27th August. Powerhouse Museum, Sydney.
Chattopdhyay, G., Hallahan, P., Brockbank, P., Lestari, F., Hayes, A. and Green, A. (2004). Development of a new apparatus for the assessment of health impact from exposure to fire combustion products. Oral Presentation. TechTrain 2004 conference. TechNet South Australia, 1-2 July 2004, The University of Adelaide.
Azzi, R. Winder, C. Khalil. C. and Hayes, A. (2004). Comparative analysis of selected in vitro cytotoxicity assays for use in standard setting of industrial chemicals. 10th International Congress in Toxicology, June 2004, Finland.
Lestari, F., Hayes A., Green, A., Chattopadhyay G., Khalil C. and Markovic, B. (2004). Cytotoxicity assessment of smoke from polymer combustion on human cells. The Australian Society for Medical Research, XIIIth NSW Scientific Meeting. 7th June 2004, Sydney.
Lestari, F., Green, A., Hayes A., Chattopadhyay G., Khalil C. and Markovic, B. (2004). In vitro cytotoxicity test on human cells for assessment of fire combustion products using a Tube furnace. Oral presentation. 6th Asia-Ocenia Symposium Fire Science and Technology. 17-20 March, 2004, Daegu, Korea.
Hayes, A. (2003). Invited Speaker. Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT), 30 November – 3 December 2003, Sydney.
Lestari, F., Green, AR, Hayes, AJ, and Markovic, B. (2003). The In vitro cytotoxicity method for exposure of human cell lines to fire combustion products. Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT), 30 November – 3 December 2003, Sydney.